THE STUDY OF THE ACTION OF ANTIBIOTICS ON THE CAUSATIVE AGENT OF SILKWORM NOSEMATOSIS

Abstract

Fighting against the nosematosis of the silkworm is very difficult due to the fact that it is inherited. The development of effective therapeutic and preventive measures is an important problem of sericulture. The following research is aimed at studying the effect of new-generation antibiotics on the causative agent of silkworm nosematosis in the case of early diagnosis, which leads to the suspension of the pathogen development in the host organism, preserving the maximum number of caterpillars and the optimal yield of cocoons on silkworm feeding. Modern antibiotic preparations of different concentrations were tested during the research. The studies were carried out at the caterpillar phase by feeding them mulberry leaves sprinkled with drugs and at the grain phase by treating the slightly infected grain in solutions. The intensity of infection with nosematosis in the experimental variants when compared with the control variant is 33.5%. After feeding the caterpillars for the first 5 days of the V-th age, leaves treated with antibiotics, a decrease in the infection intensity by 9.5-18.0 absolute percent is determined. The greatest decrease in the extent of infection is observed in the variants with the preparations Sinurol 1,2 million units, Sinurol 2,4 million units, Metronidazole (750 and 500 mg), Ciprofloxacin (250 mg), and it amounted to 14,0-18,0 abs.%. The results are consistent with published data indicating that antibiotics have an inhibitory effect against parasitic protozoa, which include the causative agent of silkworm nosematosis.